Yes! Thank you so much! I tried this out and, yeah, the syscard3.pce goes into the folder with your roms and you should edit the .cue in notepad and make sure that it directs to the iso or bin file letter for letter.
So thank you, Mutex and thanks again, karloss. I had a Sega Cd and (briefly) a Turbo Duo back in the day, so it’s really cool to get to play some of these great games on my TV again.