Ok, this isn’t 16-bit, but for the sake of making a billion posts for splash screens of mine, I’ll post it here.
Here’s Tetris for Gameboy. It’s pixel, but done differently than others since the Gameboy has such a tiny resolution. So I put pixel separation and a slight glow around the edges of the separation to emulate the LCD screen. And sampled colors from photos of a Gameboy screen. So hopefully they’re accurate.